DescriptionOverview RTI is a leader in multi-disciplinary research to address complex problems that impact human health. A historical strength, led by RTIโs Exposure and Protection (E&P) Group, has been its focus on inhalation exposure assessment and corresponding effects on human health through basic and applied research. Our research program focuses on advancing the understanding of pulmonary biology and disease mechanisms through innovative research and cutting-edge technologies. Our research focuses on investigating cellular and molecular pathways, developing predictive in vitro models, and building 3D tissue models for drug discovery. These are complemented by strong collaborations in exposure measurement and modeling, particle and chemical speciation, computational modeling, data analytics, and therapeutic drug delivery. We are seeking to grow our research program in in vitro approaches to inhalation toxicology testing and respiratory disease mechanisms. To help grow these efforts, we are Tissue Engineering Technician with excellent cell biology skills to contribute to this exciting area of research. The ideal candidate will be highly motivated, detail-oriented, and have a passion for applying cellular and molecular biology expertise to tissue engineering innovations. This position provides an opportunity to work collaboratively in a dynamic research environment while supporting projects that bridge fundamental science and translational applications. The Tissue Engineering Technician will also provide administrative and logistic support for laboratory research operations and project management. Responsibilities You will work closely with senior researchers in various areas, including Cell Biology & Tissue Engineering, where you will perform advanced cell culture, particularly with primary human endothelial and epithelial cells, to develop and maintain 3D co-culture systems. You will also conduct molecular and cellular assays, such as viability/cytotoxicity assays, immunostaining, qPCR, ELISA, and western blotting, to evaluate cellular responses in engineered tissues. Additionally, you will help characterize the development and function of tissue-engineered models, focusing on aspects like barrier integrity, signaling pathways (e.g., NF-kB), and extracellular matrix remodeling. In terms of Research & Innovation, you will assist in developing in vitro vascular and respiratory models for disease mechanism studies, therapeutic testing, and environmental exposure analyses, while contributing to the integration of data-driven approaches for biomarker discovery and analysis. For Lab Operations, you will manage lab equipment, maintain inventory, and ensure smooth day-to-day operations. You will also help develop and refine standard operating procedures (SOPs) for tissue preparation and cell-based assays. Finally, in terms of Collaboration & Communication, you will collaborate with interdisciplinary teams, including data scientists, engineers, and external academic and industry partners, and actively participate in lab meetings, present data, and contribute to manuscript preparation and grant writing efforts. Qualifications Bachelorโs degree in biomedical engineering, biology, or a related field with strong cell biology experience. Applicants must have 2โ5 years of hands-on experience in academic or industry settings working with mammalian cell cultures. Expertise in mammalian cell culture, including primary and immortalized cells, with a preference on experience in human cell-based systems. Proficiency in cellular and molecular biology techniques, including ELISA, qPCR, immunofluorescence, and protein assays. Strong organizational skills, attention to detail, and the ability to independently plan and execute experiments. Effective communication, time management, and interpersonal skills to thrive in a collaborative research environment. Preferred Qualifications: Experience with tissue engineering and/or co-culture techniques. Familiarity with developing 3D tissue models for vascular or pulmonary research. Knowledge of statistics and data analysis tools for interpreting experimental results. Prior experience contributing to research publications or grant proposals. Exposure to machine learning or computational approaches for data-driven biomarker discovery. EEO & Pay Equity Statements For San Francisco, CA USA Job Postings Only: Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records. Further information is available here. RTI accepts applications to our job openings from candidates with criminal histories or conviction records in accordance with all applicable laws, including the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act. For Applicants in Massachusetts Only: It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. The anticipated pay range for this role is listed below. Our pay ranges represent national averages and may vary by location as a geographic differential may be applied to some locations within the United States. RTI considers multiple factors when making an offer including, for example: established salary range, internal budget, business needs, and education and years of work experience possessed by the applicant. Further, salary is merely one element to our offer. At RTI, we demonstrate our commitment to rewarding individual and team achievement through a total rewards package. This package includes (among other things) a competitive base salary, a generous paid time off policy, merit based annual increases, bonus opportunities and a robust recognition program. Other benefits include a competitive range of insurance plans (including health, dental, life, and short-term and long-term disability), access to a retirement savings program such as a 401(k) plan, paid parental leave for all parents, financial assistance with adoption expenses or infertility treatments, financial reimbursement for education and developmental opportunities, an employee assistance program, and numerous other offerings to support a healthy work-life balance. Equal Pay Act Minimum/Range $70,000 - $87,000
ResponsibilitiesYou will work closely with senior researchers in various areas, including Cell Biology & Tissue Engineering, where you will perform advanced cell culture, particularly with primary human endothelial and epithelial cells, to develop and maintain 3D co-culture systems. You will also conduct molecular and cellular assays, such as viability/cytotoxicity assays, immunostaining, qPCR, ELISA, and western blotting, to evaluate cellular responses in engineered tissues. Additionally, you will help characterize the development and function of tissue-engineered models, focusing on aspects like barrier integrity, signaling pathways (e.g., NF-kB), and extracellular matrix remodeling. In terms of Research & Innovation, you will assist in developing in vitro vascular and respiratory models for disease mechanism studies, therapeutic testing, and environmental exposure analyses, while contributing to the integration of data-driven approaches for biomarker discovery and analysis. For Lab Operations, you will manage lab equipment, maintain inventory, and ensure smooth day-to-day operations. You will also help develop and refine standard operating procedures (SOPs) for tissue preparation and cell-based assays. Finally, in terms of Collaboration & Communication, you will collaborate with interdisciplinary teams, including data scientists, engineers, and external academic and industry partners, and actively participate in lab meetings, present data, and contribute to manuscript preparation and grant writing efforts
QualificationBachelorโs degree in biomedical engineering, biology, or a related field with strong cell biology experience. Applicants must have 2โ5 years of hands-on experience in academic or industry settings working with mammalian cell cultures. Expertise in mammalian cell culture, including primary and immortalized cells, with a preference on experience in human cell-based systems. Proficiency in cellular and molecular biology techniques, including ELISA, qPCR, immunofluorescence, and protein assays. Strong organizational skills, attention to detail, and the ability to independently plan and execute experiments. Effective communication, time management, and interpersonal skills to thrive in a collaborative research environment. Preferred Qualifications: Experience with tissue engineering and/or co-culture techniques. Familiarity with developing 3D tissue models for vascular or pulmonary research. Knowledge of statistics and data analysis tools for interpreting experimental results. Prior experience contributing to research publications or grant proposals. Exposure to machine learning or computational approaches for data-driven biomarker discovery